Penicillin Cocktail

5 from 5 votes
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There’s never been a better time than now to post something called a Penicillin cocktail. With things going the way they are of late, it felt like the perfect opportunity to share what is a very easy to make (and delicious) cocktail.

If you are looking for another easy scotch cocktail idea, try a scotch and soda. Simple can be the best sometimes!

a glass of penicillin cocktail garnished with a lemon slice, a piece of ginger and a bottle of laphroaig
Penicillin Cocktail

What is a Penicillin Cocktail?

The Penicillin cocktail was created in 2005 by Sam Ross at Milk & Honey, a bar in New York City, the Penicillin cocktail is a great example of how well scotch works within cocktails. The combination of blended scotch with the smokiness of a good Islay whisky works perfectly in this drink.

How to Make a Penicillin Cocktail

This drink requires two types of scotch; blended scotch and one from Islay (for the peated, smoky flavor) and some ginger simple syrup. To make this drink, combine the ingredients (minus the Islay scotch) in a shaker and shake until cold. Pour over a large ice cube in a whisky tumbler and float the Islay scotch on top. Garnish with a lemon slice or a piece of candied ginger and serve. If you like this drink; try my Pineapple Peat cocktail as well.

Penicillin Cocktail

This drink works wonders for a sore throat and a dry cough so if you need something to help soothe the old throat before bed (or heck, whenever you feel like it really) then this is the cocktail for you. I’ve linked to the recipe for my ginger simple syrup above as well for those who are wondering how to make it.

I hope you enjoy!



Penicillin Cocktail pin

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Penicillin Cocktail

A delicious cocktail that's perfect for a sore throat or dry cough (or if you just like the taste of honey and smoke!
5 from 5 votes
Penicillin Cocktail
Prep Time
5 minutes
Total Time
5 minutes
Karlynn Johnston


  • 2 ounces blended Scotch
  • 1/4 ounce Scotch from Islay (peated)
  • 3/4 ounce lemon juice fresh is best
  • 3/4 ounce honey ginger simple syrup see recipe


  • Combine all ingredients except the Islay scotch in a shaker with ice and shake until cold.
  • Pour over a large ice cube into a whisky tumbler.
  • Float the Islay scotch on top of the drink and serve.

Nutrition Information

Calories: 221kcal, Carbohydrates: 17g, Protein: 1g, Fat: 1g, Saturated Fat: 1g, Sodium: 13mg, Sugar: 16g, Vitamin C: 8mg, Iron: 1mg

All calories and info are based on a third party calculator and are only an estimate. Actual nutritional info will vary with brands used, your measuring methods, portion sizes and more.

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Mr. Kitchen Magpie

Hey everyone! I'm Mike (Mr. Kitchen Magpie). When I'm not sharing cocktail recipes here and on my Instagram (@mrkitchenmagpie), I'm enjoying a nice bottle of scotch in a vintage glass from my barware collection.

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Reader Interactions

Comments & Recipe Tips Share a tip or comment!

  1. Alice says

    I have followed you for a while and am a fan. That being said, I’m disappointed that you used the word “scare”. This is real, we are headed for trouble and your language minimizes the problem we face.

    Please think carefully.

    • Mike Johnston says

      Fair point, while the verbiage wasn’t intended to downplay things, We’ve already pulled our kids from school and have been mentioning how serious we are treating this but I do see how it can come across as dismissive using that wording. I’ve adjusted the text accordingly. Thanks for mentioning it.5 stars

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